What is Butalbital ?
Butalbital belongs to the drug class of sedative-hypnotics. It is a barbiturate with intermediate onset and duration of action. Butalbital and talbutal have the same chemical formula but a slightly different structure.
It is not recommendable as a single agent, but it is available in combination with acetaminophen or aspirin (acetylsalicylic acid). Fioricet is the brand version containing a mixture of butalbital and acetaminophen. Fiorinal is the brand version containing the combination of butalbital and acetylsalicylic acid or aspirin.
Buy Butalbital online for the management of pain and vascular headaches. People also Order Butalbital online for treating the symptoms of complex tension or muscle contraction. Butalbital is helpful when treatment from other medications such as non-opioids and opioids is not adequate or sufficient.
The medication exhibits muscle relaxant and anti-anxiety properties, capable of producing CNS mood alteration ranging from excitation to mild sedation, hypnosis, and even coma.
How Butalbital Works?
Butalbital is a central nervous system (CNS) depressant. It suppresses impulsion conduction, neuronal excitability, and release of neurotransmitters. It works similarly like other barbiturates. Butalbital primarily mediates suppressive actions by diminishing facilitation and enhancing inhibition. It may also inhibit excitatory effects.
Absorption and elimination of Butalbital :
Butalbital gets quickly absorbed by the gastrointestinal tract. It reaches peak concentration in the blood within approximately 2 hours.
The drug undergoes renal elimination, with 60 to 88% of the total dose excreted from kidneys. The plasma half-life of Butalbital is about 35 hours.
What are the preparations for Butalbital?
Butalbital is available in the following combinations:
- Butalbital and acetaminophen or paracetamol: Axocet, Bucet, Bupap, Cephadyn, Dolgic, Phrenilin, Forte, and Sedapap.
- Butalbital and acetaminophen plus caffeine: Esgic, Esgic-Plus, and Fioricet.
- Butalbital and aspirin: Axotal
- Butalbital and aspirin plus caffeine: Fiormor, Fiortal, Fortabs, Laniroif, and Fiorinal.
- Butalbital and acetaminophen, caffeine plus codeine phosphate: Fioricet#3.
- Butalbital and aspirin, caffeine, plus codeine phosphate: Fiorinal #3.
- Butalbital and Ergotamine tartrate, caffeine, plus belladonna alkaloids: Cafergot-PB.
What are the side effects of Butalbital ?
Butalbital impairs alertness, possess a risk of dependence and addiction, and elevates the risk of episodic headaches becoming chronic. The common side effects of Butalbital use include:
- Nausea and vomiting
- Respiratory tract infection
- Muscle pain
- Back pain
- Menstrual cramps
- Feeling intoxicated
- Sedative state
More severe but less frequent side effects of Butalbital include:
- Increased heart rate
- Feelings of shakiness
- Acute fever
- Heavy eyelids
- Hot spells
- dry mouth
- Difficulty swallowing
- Leg pain
- Muscle fatigue
- Increased urination
- Ringing in ears
- Stuffy nose
- Pain in ear
- Severe itching
- Allergic reactions.
What is the dependency of Butalbital?
Butalbital is a sedative-hypnotic and a habit-forming drug. It produces both tolerance and dependence. The dependency of Butalbital leads to its addiction, abuse, and misuse. Butalbital is a central nervous system depressant and causes high in the abusing person.